COLEMAN BREAKS HAND: Cleveland Browns rookie wide receiver Corey Coleman broke his hand during practice Wednesday, another major blow to the struggling team.

Coleman's injury comes on the heels of the Browns losing starting quarterbacks Robert Griffin III and Josh McCown in the first two weeks this season.

They also lost starting center Cam Erving with a bruised lung and promising rookie defensive end Carl Nassib with a broken hand in Sunday's loss to Baltimore.

Coleman scored two touchdowns against the Ravens and was finally looking like a big-time playmaker the Browns envisioned he could be when they drafted him in the first round.

ABDULLAH ON IR: Theo Riddick is about to get a chance to be an every-down running back in the NFL.

The Detroit Lions put running back Ameer Abdullah on the reserve-injured list with a foot injury Wednesday, keeping him out of the lineup for at least eight weeks and pushing Riddick up the depth chart.

Abdullah hurt his left foot on a 24-yard run in the second quarter of a loss Sunday to Tennessee and didn't return to play. The 2015 second-round pick ran for 101 yards on 18 carries and had five receptions for 57 yards and a touchdown for the Lions (1-1) this season.

SEAHAWKS HOPEFUL: The Seattle Seahawks are optimistic injured offensive starters Doug Baldwin, Tyler Lockett and Thomas Rawls will be able to play Sunday against San Francisco.

Coach Pete Carroll said Wednesday that all three have a chance of being available after suffering injuries in the Seahawks' Week 2 loss at Los Angeles. Baldwin and Lockett suffered minor knee injuries, while Rawls has a muscle strain in his left leg. Carroll seemed most pessimistic about Rawls, whom he said would be limited in practice early in the week.

MONCRIEF SIDELINED: Indianapolis Colts receiver Phillip Dorsett may be about to get his first big opportunity in the NFL.

The 2015 first-round draft pick will be asked to play a much bigger role over the next month — and perhaps longer — after learning No. 2 receiver Donte Moncrief will miss four to six weeks with a fractured left shoulder blade.

Moncrief was injured in the first quarter of Sunday's loss at Denver and did not return, another big blow for a team already hit hard by injuries.

CHARLES IS CLOSE: Kansas City Chiefs coach Andy Reid called the prognosis of Jamaal Charles "all positive" on Wednesday, increasing the likelihood that the injured running back finally will get on the field this weekend.

Charles has not played since Week 5 last season, when he tore the ACL in his right knee. He was back on the field for training camp and has been splitting time with the scout team and first team in practice, but the four-time Pro Bowl selection has not been active for a game.

Spencer Ware and Charcandrick West have been filling in for him .

BOSA IN PADS: Joey Bosa has practiced in pads for the first time with the San Diego Chargers, although he was limited in his work Wednesday.

Now the big question — when will the first-round draft pick make his NFL debut?

Bosa, who missed all of training camp due to a contract dispute, wouldn't venture a guess, saying only that he's day-to-day.

HOYER IS NO. 1: Brian Hoyer is preparing to start at quarterback for the Chicago Bears against the Dallas Cowboys.

Jay Cutler missed practice Wednesday with the sprained right thumb he suffered Monday night.

Although the team isn't saying Cutler is out for Sunday night's game, Hoyer is taking all the snaps in practice with the first team.